Database : HANSEN Search on : TESTES INTRADERMICOS [Subject descriptor] References found : 11 [refine] Displaying: 1 .. 11   in format [Detailed]

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Id: 16832 Author: Arnold, Harry L. Title: The intradermal mecholyl test for anidrosis; a diagnostic aid in leprosy. Source: Int. J. Lepr;16(3):335-346, Jun.-Sept. 1948. tab. Abstract: Sweat glands, though of sympathetic innervation, have acetylcholine as their chemical mediator, and normally they respond directly to that substance upon its injection. Metacholine (acetylbeta-methyl choline) or its chloride has the same effect on sweat glands as acetylcholine or its chloride. Removal or destruction of the post-ganglionic sympathetic nerves, resulting in denervation of the sweat glands, prevents them from responding to acetylcholine or metacholine. The reason for this is not known. It seems probable that one of the earliest consequences of tuberculoid leprosy in the skin is the denervation of sweat glands, and that this is an eventual consequence of leprosy of either type involving nerve trunks. The intradermal injection of metacholine chloride, therefore, frequently gives evidence of peripheral sympathetic nerve damage by showing loss of the normal sweat response. This manifestation may be interpreted as iniciative of leprosy in cases in which no equally cogent evidence to the contrary can be adduced, and may further be interpreted as indicative of nerve-damaging (i.e. tuberculoid) leprosy when it shows anidrosis which is coextensive with the visible skin lesion. Failure or marked diminution of the sweat response is frequently observed in facial lesions of so-called achromia parasitica, and occasionally in the normal skin of the face as well. The greatest advantage of the sweating test over the histamine test is that its results may be read with ease even in darkskinned patients. (AU). Descriptors: HANSENIASE HANSENIASE/diag TESTES INTRADERMICOS/clas TESTES INTRADERMICOS/util Electronic Medium: http://www.ilsl.br Location: BR191.1

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Id: 13462 Author: Bach, Marie Anne; Chatenoud, Lucienne; Wallach, D; Phan Dinh Tuy, Françoise; Cottenot, F Title: Studies on T cell subsets and functions in leprosy ..- Source: s.l; s.n; jun. 1981. 10 p. tab, graf. Abstract: T cell subsets and T cell functions were explored in 31 leprosy patients with the following methods: determination of the percentages of the different T cell subpopulations defined by monoclonal antibodies directed at total T cells, helper T cells and suppressor/cytotoxic T cells; measurement of the in vitro proliferative responses to mitogens; study of the concanavalin A-induced suppressive activity, assessed on MLC; measurement of delayed-type hypersensitivity by skin testing. The confrontation between immunological lepromatous patients without type-2 reaction (erythema nodosum leprosum), (2) lepromatous patients without ENL (erythema nodosum leprosum), (2) lepromatous patients was recent ENL and (3) tuberculoid patients. Unexpectedly, groups 1 and 3, although differing strongly in their clinical status and their sensitivity to lepromin (absent in group 1 and strong in group 3), showed a similar immunological profile with a normal percentage of T cells and a normal distribution of T cells among the major T cell subset contrasting with a moderate decrease of proliferative responses to mitogens and impaired delayed-type hypersensitivity reactions. Concanavalin A-induced suppressive activity was type-2 reaction) strongly differed from both other groups, showing striking abnormalities other groups, showing striking abnormalities of the repartition of the T cell subsets, with increased percentages of helper T cells and decreased percentages of suppressor T cells, and elevated proliferative responses to mitogens. Concanavalin A-induced suppressive activity was reduced in most patients of this group. It is suggested that this imbalance between T cell subsets contributes to the occurrence of ENL reactions in lepromatous patients.(AU). Descriptors: ANTICORPOS MONOCLONAIS/imunol HANSENIASE/imunol TESTES INTRADERMICOS CONTAGEM DE LEUCOCITOS TRANSFORMACAO LINFOCITICA LINFOCITOS T/clas LINFOCITOS T/imunol LINFOCITOS T SUPRESSORES-EFETORES/imunol CONCANAVALINA A/farmacol Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE IDOSO SUPPORT, NON-U.S. GOV'T ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01450/s

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Id: 13268 Author: Bach, Marie-Anne; Chatenoud, Lucienne; Wallach, D; Phan Dinh Tuy, F; Cottenot, F Title: Studies on T cell subsets and functions in leprosy ..- Source: s.l; s.n; jun. 1981. 10 p. tab, graf. Abstract: T cell subsets and T cell functions were explored in 31 leprosy patients with the following methods: determination of the percentages of the different T cell subpopulations defined by monoclonal antibodies directed at total T cells, helper T cells and suppressor/cytotoxic T cells; measurement of the in vitro proliferative responses to mitogens; study of the concanavalin A-induced suppressive activity, assessed on MLC; measurement of delayed-type hypersensitivity by skin testing. The confrontation between immunological lepromatous patients without type-2 reaction (erythema nodosum leprosum), (2) lepromatous patients without ENL (erythema nodosum leprosum), (2) lepromatous patients was recent ENL and (3) tuberculoid patients. Unexpectedly, groups 1 and 3, although differing strongly in their clinical status and their sensitivity to lepromin (absent in group 1 and strong in group 3), showed a similar immunological profile with a normal percentage of T cells and a normal distribution of T cells among the major T cell subset contrasting with a moderate decrease of proliferative responses to mitogens and impaired delayed-type hypersensitivity reactions. Concanavalin A-induced suppressive activity was type-2 reaction) strongly differed from both other groups, showing striking abnormalities other groups, showing striking abnormalities of the repartition of the T cell subsets, with increased percentages of helper T cells and decreased percentages of suppressor T cells, and elevated proliferative responses to mitogens. Concanavalin A-induced suppressive activity was reduced in most patients of this group. It is suggested that this imbalance between T cell subsets contributes to the occurrence of ENL reactions in lepromatous patients.(AU). Descriptors: ANTICORPOS MONOCLONAIS/imunol CONCANAVALINA A/farmacol TESTES INTRADERMICOS HANSENIASE/imunol CONTAGEM DE LEUCOCITOS TRANSFORMACAO LINFOCITICA LINFOCITOS T/clas LINFOCITOS T/imunol LINFOCITOS T SUPRESSORES-EFETORES/imunol Limits: HUMANO MASCULINO FEMININO ADULTO MEIA-IDADE IDOSO SUPPORT, NON-U.S. GOV'T ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 01569/s

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Id: 13232 Author: Girdhar, B. K; Desikan, K. V Title: Results of skin tests with five different mycobacteria ..- Source: s.l; s.n; oct. 1978. 5 p. ilus, tab. Abstract: A comparison of intradermal response to injection of Dharmendra type of coded antigens, prepared from different species of Mycobacteria by Prof. G.P. Talwar has been made over 3 weeks period. The results are reported.(AU). Descriptors: ESTUDOS DE AVALIACAO HANSENIASE/imunol HANSENIASE/microbiol MYCOBACTERIUM/imunol MYCOBACTERIUM LEPRAE/imunol MYCOBACTERIUM PHLEI/imunol ANTIGENOS DE BACTERIAS/admin ANTIGENOS DE BACTERIAS/imunol TESTES INTRADERMICOS Limits: ESTUDO COMPARATIVO HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 02119/s

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Id: 13231 Author: Mustafa, A. S; Talwar, G. P Title: Delayed hypersensitivity skin reactions to homologous and heterologous antigens in guinea-pigs immunized with M. leprae and four selected cultivable mycobacterial strains ..- Source: s.l; s.n; oct. 1978. 11 p. tab. Abstract: Guinea-pigs were immunized with Mycobacterium leprae in saline and with autoclaved preparations of Mycobacterium w., ICRC bacillus, Mycobacterium phlei and Mycobacterium vaccae. A group of animals were also immunized with live Mycobacterium w. All animals were challenged after one month of M. leprae and other mycobacteria. Induration produced in response in guine-pigs to challenge with homologous mycobacterial preparations and M. leprae. In most cases, the early reaction was higher with homologous antigens as compared to M. leprae antigens were however of comparable order especially in animals immunized with Mycobacterium w, and ICRC bacillus. Animals immunized with M. leprae gave low late reactions with preparations from Mycobacterium phlei and Mycobacterium vaccae.(AU). Descriptors: ANTIGENOS DE BACTERIAS/imunol ANTIGENOS HETEROFILOS/imunol HIPERSENSIBILIDADE TARDIA/etiol TESTES INTRADERMICOS MYCOBACTERIUM/imunol MYCOBACTERIUM LEPRAE/imunol MYCOBACTERIUM PHLEI/imunol IMUNIZACAO Limits: ESTUDO COMPARATIVO HUMANO ANIMAL COBAIAS Electronic Medium: http://www.ilsl.br Location: BR191.1; 02120/s

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Id: 13230 Author: Mustafa, A. S; Talwar, G. P Title: Early and late reactions in tuberculoid and lepromatous leprosy patients with lepromins from Mycobacterium leprae and five selected cultivable mycobacteria ..- Source: s.l; s.n; oct. 1978. 6 p. tab. Abstract: Skin reactions have been measured in tuberculoid and lepromatous leprosy patients with Dharmendra and Mitsuda type of lepromins prepared from M. leprae, Mycobacterium w, ICRC bacillus, M. phlei, M. vaccae and M.gordonae. In tuberculoid patients Mycobacterium w gave the closest response to M. leprae, however, in lepromatous and borderline lepromatous cases, this bacteria produced greater response than M. leprae. (AU). Descriptors: TESTES INTRADERMICOS ANTIGENO DE MITSUDA/imunol HANSENIASE/imunol MICOBACTERIAS ATIPICAS/imunol MYCOBACTERIUM/imunol MYCOBACTERIUM LEPRAE/imunol MYCOBACTERIUM PHLEI/imunol PELE/imunol FATORES DE TEMPO Limits: ESTUDO COMPARATIVO HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 02121/s

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Id: 10823 Author: Madeira, Jose Alcantara Title: O methodo intradermico no tratamento da lepra ..- Source: s.l; s.n; 1937. 14 p. . Descriptors: HANSENIASE TESTES INTRADÉRMICOS Location: BR191.1; 07843/s

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Id: 9974 Author: Kato, L; Szejtli, J; Szente, L Title: Water soluble complex of palmitic acid in media for cultivation of leprosy-derived psychrophilic mycobacteria from mycobacterium leprae infected tissues ..- Source: s.l; s.n; 1993. 12 p. tab. Descriptors: ANIMAIS TATUS TÉCNICA DE TIPAGEM BACTERIANA MEIOS DE CULTURA TESTES INTRADÉRMICOS HANSENIASE HANSENIASE CAMUNDONGOS MYCOBACTERIUM MYCOBACTERIUM MICOBACTERIOSE MICOBACTERIOSE MYCOBACTERIUM LEPRAE ACIDOS PALMITICOS SOLUBILIDADE TEMPERATURA AMBIENTE Location: BR191.1; 06618/s

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Id: 9544 Author: Roche, Paul W; Theuvenet, Wim J; Britton, Warwick J Title: Risk factors type-1 reactions in bordeline leprosy patients ..- Source: s.l; s.n; 1991. 4 p. tab, graf. Descriptors: ADOLESCENCIA ANTICORPOS ANTIBACTÉRIAS ANTICORPOS MONOCLONAIS MARCADORES BIOLOGICOS HIPERSENSIBILIDADE A DROGAS HIPERSENSIBILIDADE A DROGAS IMUNIDADE CELULAR TESTES INTRADÉRMICOS HANSENIASE DIMORFA HANSENIASE DIMORFA HANSENIASE TUBERCULOIDE LIPOPOLISSACARIDIOS MYCOBACTERIUM LEPRAE NEURITE NEURITE DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO FATORES DE RISCO GLICOLIPIDIOS Location: BR191.1; 06272/s

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Id: 9415 Author: Uyemura, Koichi; Ho, Christopher T; Ohmen, Jeffrey D; Rea, Thomas H; Modlin, Robert L Title: Selective expansion of VS1 + T cells from leprosy skin lesions ..- Source: s.l; s.n; 1992. 5 p. ilus, tab, graf. Descriptors: SEQUENCIA DE AMINOACIDOS VACINAS BACTERIANAS SEQUENCIA DE BASES LINHAGEM CELULAR REORDENAMENTO GENICO DO LINFOCITO T TESTES INTRADÉRMICOS HANSENIASE TUBERCULOIDE DADOS DE SEQUENCIA MOLECULAR MYCOBACTERIUM LEPRAE - FENOTIPO  RECEPTORES DE ANTIGENO DA CÉLULA-T  RECEPTORES DE ANTIGENO DA CÉLULA-T  PELE  LINFOCITOS T Location: BR191.1; 06387/s

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Id: 7023 Author: Almeida Neto, Estevam de. Title: Prova do eter na hansenologia / Ether test in leprology Source: Hansen. Int;8(1):46-53, jan. 1983. ilus. Abstract: Na intensa rotina da Secção de Elucidação Diagnóstica do antigo Departamento de Profilaxia da Lepra de São Paulo, o autor teve a idéia de utilizar o éter sulfúrico na pesquisa da sensibilidade térmica, pois este liquido entra em ebulição a 35 º c, praticamente á temperatura da pele humana e, ao fazê-lo, evidentemente promove sensação nítida de frio ou gelado, subtraindo 90 calorias por grama de éter vaporizado. Descriptors: HANSENIASE - ÉTER ETILICO  TESTES INTRADÉRMICOS  SENSIBILIDADE TÉRMICA Electronic Medium: http://hansen.bvs.ilsl.br/textoc/hansenint/v01aov20/1983/PDF/v8n1/v8n1a05.pdf / Pt Location: BR191.1

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